Vatican City is the smallest Country in the world by both area and population. An area of approximately 44 hectares (110 acres), and a population of 842. Vatican City, a city-state surrounded by Rome, Italy, is the headquarters of the Roman Catholic Church. It's home to the Pope and a trove of iconic art and architecture. Its Vatican Museums house ancient Roman sculptures such as the famed “Laocoön and His Sons” as well as Renaissance frescoes in the Raphael Rooms and the Sistine Chapel, famous for Michelangelo’s ceiling.